Two points don't have a slope.
But the line between them does.
The line between the points (-5, 3) and (3, 3) has a slope of zero.
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-5/3 it is always the opposite reciprocal for a perpendicular slope
The slope between the points (3, 5) and (-2, 2) is 3/5
Points: (1, -5) and (3, 5) Slope: 5
-5/3
Points: (-3, -10) and (5, -7) Slope: 3/8