Quite a few. However the most obvious is 17*22 = 374.
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22 Add the numbers, then divide by the number of numbers (in this case 5).
22 - 12 = 10; 10/2 = 5 = lower number so higher number = 17.
Ask what is the odd number out and why It is 17 which is a prime number
A number with 22 DIGITS (not numbers) is of the order of a sextillion.
17 + 5 = 22 17 - 5 = 12