Sickle Cell Disease can be found in patients of any nationality or decent. Both parents must carry the recessive gene for this disease, and only then their offspring have a 25% chance of inheriting the disease. Those of African decent have approximately an 8% chance of inheriting the disease, Hispanics have about a 0.07% chance of inheriting the disease, and whites have roughly a 0.001% chance of inheriting the disease.
Depran 10 (which contains hydroxyurea) is primarily used to manage sickle cell disease by reducing the frequency of painful crises and the need for blood transfusions. Etilaam (which contains etizolam) is a medication used to treat anxiety and panic disorders due to its anxiolytic and sedative properties. Both medications serve distinct therapeutic purposes: Depran 10 focuses on hemoglobin management in sickle cell patients, while Etilaam addresses mental health issues.
583 gold is 14 KT but the europeans Use 585 as the 14KT mark You will find 583 on soviet gold which is 14KT Soviet gold is stamped with a Hammer and sickle and some cyrillic underneath It has the sign of the hammer and sickle and the 583 near to it. This is the system stalin used in the time he ruled Soviet Russia The British gold office say that 585 is 14 karat when if you use the correct mathmatical equation you will find that 14 KT is actually nearer to stalins Soviet Gold Soviet gold Is Not Russian Gold just so you know folks
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Cholelithiasis refers to the formation of rock-like crystalline deposits (gallstones or biliary calculi) in the gallbladder. Development is insidious and may remain asymptomatic for years. The major component of most (approximately 85%) gallstones is cholesterol (cholesterol-predominant or "mixed" gallstones also containing calcium salts). These occur either as a solitary stone or multiple stones of varying sizes. Others stones (approximately 15%) are composed solely of calcium salts (calcium carbonate, calcium bilirubinate) or crystallized bile pigments (bilirubin). Pigment stones are more common in Asian than in Western populations. The gallbladder stores bile, a fluid that is produced in the liver to aid in the digestion of fats. Normal bile is sterile and contains a high level of cholesterol, which usually remains in liquid form. When the bile contains too much cholesterol and/or levels of cholesterol and lecithin are imbalanced, the bile becomes supersaturated. When this occurs, solid crystals of cholesterol and calcium salts form and settle out of the liquid bile creating sludge or gallstones. Other causes of cholelithiasis include production of bile that contains inadequate amounts of certain chemicals (phospholipids or bile acids) or blockage of the ducts carrying bile from the gallbladder to the intestine (biliary stasis). Obstruction can also lead to colonization of bile with bacteria, resulting in infection. Individuals with high heme turn over (e.g., cirrhosis, hemoglobinopathies including sickle cell disease, thalassemia, spherocytosis) are predisposed to bilirubin stones. United Nations Farms
Osmotic fragility usually (unless otherwise mentioned) refers to the ease with which Red Blood Cells (RBCs) undergo lysis in a hypotonic solution. Before knowing what 'low osmotic fragility' means, one should know the concept of osmotic fragility. Different parameters, some of them related to the RBC and some of the extracellular environment have an effect on osmotic fragility. Low osmotic fragility means that the RBCs have a resistance against undergoing lysis when suspended in solutions which are hypotonic. They undergo lysis only if the solution is extremely hypotonic. In contrast, high osmotic fragility refers to the tendency of the RBCs to lyse even if the solution in which they are suspended in is mildly hypotonic. As an example for low osmotic fragility would be thalassemia. And as an example for high osmotic fragility, spherocytosis (a hereditary condition where the RBCs lose their usual biconcave structure and become spherical) causes increased osmotic fragility. i.e, It very easily lyses even at solutions which are mildly hypotonic... p.s Another interesting point to note is that in sickle cell anemia, the RBCs show increased mechanical fragility but decreased osmotic fragility. Elucidated by the fact that post-splenectomy the RBC lifespan increases.
Sickle cell can not be "caught". It is an inherited genetic disease and is only in the African American community.
Not containing enough Red blood cells. From African and Indian decent. Sickle cell disease is a defective hemoglobin.
A person can only inherit sickle-cell genes if some of their ancestors came from certain regions in Africa where the inhabitants carry sickle-cell genes. A person with one sickle-cell gene has sickle-cell trait, a milder problem. If both father and mother pass on sickle-cell genes, the child, with two genes, will have sickle-cell disease.
the disease is sickle cell
hemolytic anemia and bone marrow
Sickle cell anemia is a gentic disease carried by people of African and sometimes Indian decent. Although both parents need to at least carry the gene for their children to get it not necessarily have the disease.
What is sickle cell disease?Sickle cell disease is an inherited disorder that affects red blood cells. People with sickle cell disease have red blood cells that become hard and pointed instead of soft and round. Sickle cells cause anemia, pain and many other problems.Top2) What is sickle cell trait?If you have sickle cell trait, you have inherited the gene for sickle cell disease. Sickle cell trait does not turn into sickle cell disease. If someone has sickle cell trait and his partner has sickle cell trait they may produce a child with sickle cell disease. There are about 2.5 million people in America with sickle cell trait.Top3) If sickle cell trait is not an illness, why are people tested?Babies are tested to see if they have sickle cell disease. Teens and adults are tested mainly to see if they can have a baby with the disease.Top4) What medical problems are caused by sickle cell disease?Lung tissue damage, pain episodes and stroke. The blockage of blood flow caused by sickled cells also causes damage to most organs including the spleen, kidneys and liver.Top5) How many people have sickle cell disease?Sickle cell disease is a global health problem. In the United States it is estimated that over 70,000 people have sickle cell disease. About 1,000 babies are born with the disease each year in America.Top6) How long does a person with sickle cell disease live?The average life expectancy in America has improved. It is now in the mid 40 years of age range.Top7) Are people of African descent the only group affected?No. It is also present in Portuguese, Spanish, French Corsicans, Sardinians, Sicilians, mainland Italians, Greeks, Turks and Cypriots. Sickle cell disease also appears in Middle Eastern countries and Asia.Top8) Is there a cure?There is no universal cure for sickle cell disease. Research in gene therapy, the ultimate universal cure, is currently underway.Top9) What are some promising treatment developments?The use of hydroxyurea has shown promising results on some adult sickle cell patients. It reduces the frequency of severe pain, acute chest syndrome and the need for blood transfusions.Top10) Can people with sickle cell disease live a productive life?Yes. But like all patients with chronic disease, sickle cell patients are best managed in a comprehensive multi-disciplinary program of care and a strong extended support system.
In sickle cell patients, a normal reticulocyte count is typically elevated due to the body's response to chronic hemolysis. The normal range for reticulocyte count in sickle cell patients is usually higher than in individuals without the disease, often ranging from 3% to 6%.
Sickle cell anemia
An antineoplastic drug (hydroxyurea) may prevent future episodes of priapism for patients with sickle cell disease.
No, sickle cell disease is not cancerous.
No. Sickle Cell is not an infectious disease, but is genetic.