This is easiest to understand using small numbers and the X,Y grid using the negative numbers to the left of 0 and positive to the right. By following the normal rules of multiplication, multiplying a negative number by a positive number moves the product further to the left from zero.
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Two plus 3 minus 2 times 1 squared plus 4 times 16 squared minus 4 times 2 is equal to 1,019.
44
2
18
2 times a number minus 17 plus 20 times a number minus 9 is the same as 2x - 17 + 20x - 9 = 22x - 26