The GCF is 16.
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64 and 16's highest common factor is 16.
The GCF of 8, 16, and 64 is 8. Since 8 is a factor of both 16 and 64, it is clearly the greatest common factor of the three.
The LCM of 16 and 64 is 64. Since 16 is a factor of 64, 64 is automatically the LCM of the pair.
The factors of 16 are 1, 2, 4, 8, and 16. The factors of 64 are 1, 2, 4, 8, 16, 32, and 64. The common factors are 1, 2, 4, 8, and 16. The least (smallest) common factor is 1. The smallest common prime factor is 2.
The GCF is 4.