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Q: Factors affectings upregulation and downregulation
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What is drug upregulation and drug downregulation?

Seems like it could be referring to up/down regulation of the receptors in your brain that give you effects from drugs. Downregulation is a way for your brain to adjust/protect itself. also.. I'm da ish trick what what


How goserelin works on downregulation of gnrh?

Goserelin is an GnRH receptor agonist and bings stronger than GnRH. Due to the constant activation of the GnRH receptor (Goserelin binds really strong; Superagonist) the cell internalizes the receptor -> Downregulation.


Is it possible to get pregnant whilst on downregulation with buserelin?

it hasn't been tried yet... or so im told


How might the production of a hormone affect the expression of genes in a eukaryotic cell?

Production of a hormone can affect gene expression in a eukaryotic cell by binding to specific receptor proteins, leading to activation of signaling pathways that influence transcription of certain genes. This can result in either upregulation or downregulation of gene expression, ultimately affecting cellular processes and functions.


What is the tolerance to steroids?

Steroid abuse can cause downregulation of the Androgen Receptor, therefore reducing the effects of testosterone and other androgens in vivo.


How the presence of a cancerous tumor affect the biological processes?

Cancerous tumours are formed from cells which have had mutations in very specific genes which have allowed them to survive independantly of cells around them in the body. Some of these key genes code for growth factors and other proteins which affect normal body cells. Often the tumour cell mutations cause upregulation of these growth factors causing neighbouring healthy cells to be affected in unusual ways.


How does thyroid effect your body?

== == Thyroid hormones have far more than just three effects on the body. Two major ones are (1) the upregulation of an electrolyte pump called the sodium-potassium pump and (2) synergism with the sympathetic nervous system.


How does LPR impact the immune system?

Laryngopharyngeal reflux (LPR) refers to a relatively common disease in which gastric contents are refluxed into part of the upper GI tract and respiratory pathway. Studies have shown that the presence of LPR causes an upregulation of antibody secreting mucosal cells and stimulation of lymphoid tissue.


What is the mechanism of olfactory adaptation?

Olfactory adaptation occurs when prolonged exposure to a specific odor causes a decrease in sensitivity to that odor. This is believed to happen through a downregulation of olfactory receptors, desensitizing the sensory neurons and reducing the perception of the odor. It helps the olfactory system to prioritize new or changing smells for detection.


What is the general phenomenon of receptor upregulation?

Up regulation is the process when there is an increase of receptors on the surface of cells making them more sensitive to agents such as hormones. This is generally associated with pregnancy because hormone levels vary all the time. Up regulation activity increases signalling the cells to prepare for labor and delivery.


What is it called when a hormone is present in excessive levels the number of target cells receptors may decrease?

Downregulation is the process in which the number of target cell receptors decreases in response to excessive levels of a hormone. This can help maintain homeostasis by reducing the cell's sensitivity to high hormone levels.


The role of a metabolite that controls a repressible operon is to?

Function as a corepressor that binds to the repressor protein and activates it to bind to the operator region of the operon. This binding prevents RNA polymerase from transcribing the operon genes, leading to the downregulation of gene expression.