The closest would be Phoenix, Arizona with 516.7 sq miles. Houston, TX is 599.6 square miles.
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The city of Houston covers an area of 601.7 square miles (1,558 km2)
It is about 5,000 miles from Houston, Texas to the Equator. If a person travels on land from Houston, Texas to Panama City, Panama and then charters a boat from Panama City, Panama to the Equator, it will shorten the trip by about 500 miles.
Waco is closer at 201 miles and the distance to Houston is 260 miles.
It is 24.3 miles according to Google Maps.
It is 1,914.95 miles according to MapQuest.