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The Lancet published a paper in 2009 titled "Comparative efficacy and acceptability of 12 new-generation antidepressants: a multiple-treatments meta-analysis" where the researchers found that the best antidepressants are Zolfot (sertraline) and Lexapro (escitalopram) in terms of efficacy and acceptability. Sertraline is not as effective as escitalopram but is available as a generic so, depending on your insurance, is less costly.

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Q: What is the strongest antidepressant?
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