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Add a liquid to the blood that can't be transported out of the lining of the blood vessels. Give it time to spread through the body. Then, take a blood sample and measure the percentage of the liquid in the blood. From the result, the blood volume can be estimated.

total blood volume = ((1 - percentage)/percentage) x amount of liquid added

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14y ago
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6mo ago

Blood volume can be indirectly estimated by measuring the hematocrit level, which represents the proportion of red blood cells in the blood. Another indirect method is through dilution techniques using a known volume of a tracer substance that gets evenly distributed in the blood plasma, allowing for calculation of the total blood volume based on the dilution factor.

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Q: How do you measure the blood volume indirectly?
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