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Dopamine is a neurotransmitter that acts as both a vasoconstrictor and vasodilator depending on the dose. At low doses, dopamine preferentially dilates blood vessels in the kidneys, mesentery, and heart, while at higher doses, it primarily constricts blood vessels systemically.
No, North Carolina did not observe Daylight Savings Time in 1948. The state of North Carolina did not consistently observe Daylight Savings Time until it was made a federal law in the Uniform Time Act of 1966.
Louis Pasteur discovered vaccination in the mid-19th century through his experiments on protecting animals from disease by exposing them to weakened forms of the pathogen. His discovery was driven by the need to find a way to prevent infectious diseases like rabies and anthrax that were causing widespread suffering and death in humans and animals at the time. His work laid the foundation for modern immunology and has since saved countless lives through the development of vaccines for various diseases.