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As of the mid-2017, Charleston slightly grew larger than Columbia. If you hear anyone say Greenville is the biggest, they may be referring to the metropolitan area. Charleston does have the smallest metro area out of the three main cities of South Carolina.

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6y ago
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3mo ago

The biggest city in South Carolina is Columbia. It is the state capital and the second-largest city in the state.

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Q: What is the biggest city in SC?
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