In hypokalemic PP, the level of potassium in the blood falls in the early stages of a paralytic attack, while in hyperkalemic PP, it rises slightly or is normal.
The gene for hyperkalemic PP affects virtually all who inherit it, with no difference in male-vs.-female expression.
Hyperkalemic PP is also called potassium-sensitive PP.
Weakness usually lasts less than three hours, and often persists for only several minutes. The attacks are usually less severe, but more frequent, than those of the hypokalemic form.
The normal gene is responsible for a muscle protein controlling the flow of sodium during muscle contraction.
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There are two major forms, hypokalemic and hyperkalemic, each caused by defects in different genes.
Periodic paralysis disorders are genetic disorders that affect muscle strength. There are two major forms, hypokalemic and hyperkalemic, each caused by defects in different genes.
The gene for hyperkalemic PP affects virtually all who inherit it, with no difference in male-vs.-female expression.
The gene for hyperkalemic PP affects virtually all who inherit it, with no difference in male-vs.-female expression.
Hyperkalemic PP is also called potassium-sensitive PP.
With hypokalemic periodic paralysis an attack of weakness can be induced by administering glucose and insulin with exercise. These tests are potentially hazardous and require careful monitoring.
The level of potassium in the blood rises slightly or is normal.
Weakness usually lasts less than three hours, and often persists for only several minutes. The attacks are usually less severe, but more frequent, than those of the hypokalemic form.
The level of potassium in the blood falls in the early stages of a paralytic attack.
An attack of hyperkalemic PP can be induced with administration of potassium after exercise during fasting. These tests are potentially hazardous and require careful monitoring.
The gene for hypokalemic PP is present equally in both sexes, but leads to noticeable symptoms more often in men than in women.
The gene for hypokalemic PP is present equally in both sexes, but leads to noticeable symptoms more often in men than in women.