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Viruses are the smallest microbes known that cause disease. They are sub-microscopic. This means that they can not be seen with a regular microscope because they are too small (measured in nanometers). It takes an electron microscope to see a virus particle.

The second microbe that is among the smallest would be bacteria and then probably protists, as a generalization, after that (protists and bacteria have wider ranges of sizes than viruses). Bacteria are microscopic living organisms, while the viruses are non-living sub-microscopic organisms. Protists are single-celled living organisms, such as protozoa.

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12y ago
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6mo ago

The smallest known microbe is a type of bacteria called Mycoplasma genitalium, which has a size of about 200-300 nanometers. It has one of the smallest known genomes of any free-living organism.

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Q: What is the smallest microbe?
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What is the world's smallest living thing?

The smallest living organism is Nanoarchaeum equitans. This minuscule microbe was only recently discovered in a hydrothermal vent off the coast of Iceland and its cells are only 400 nanometres across.


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