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If you are referring to the efficacy as anti-depressants, there is no definitive answer, each manufacturer studies shows their product to be superior to competitors. It is believed that Escitalopram (US: Lexapro, EU: Cipralex) and Paroxetine (US: Paxil, EU: Seroxat) are very powerful.

If you are referring to receptor binding potency, then studies in rats show that the strongest SSRIs are Paroxetine and Sertraline. http://www.preskorn.com/books/ssri_s3.html

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βˆ™ 13y ago
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βˆ™ 5mo ago

In terms of potency, SSRIs (selective serotonin reuptake inhibitors) do not have a clear hierarchy of strength. Different SSRIs may work better for different individuals based on factors like their specific symptoms and tolerability. Commonly prescribed SSRIs include fluoxetine (Prozac), sertraline (Zoloft), and escitalopram (Lexapro).

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Q: What is the strongest ssri?
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