50/4000 = 0.0125 = 1.25%
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There are 1000 grams in one kilogram, therefore there are 4000 grams in four kilograms.
6 grams is 0.6% of 1000 grams.
To convert 0.45 grams to a percentage, you would need to know the total mass or volume of the substance in which the 0.45 grams is a part of. Once you have the total mass or volume, you can divide 0.45 grams by the total mass or volume and then multiply by 100 to get the percentage.
There are 22,680 grams in 50 pounds.
You need 50 g of this drug.