In 1679 after suffering numerous tragedies involving his mother and children. The exact date i don't know
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Sir Isaac newton is not known to have had a nervous breakdown. However, he did suffer from periods of intense stress and anxiety, especially towards the end of his life.
Isaac Newton formulated the laws of motion. These should not be confused with the laws of planetary motion by Keplar
Sir Isaac newton
In the case of Sir Isaac Newton, "Sir" is an honorary title that signifies knighthood. Newton was knighted in 1705 by Queen Anne of England.
Sir Isaac newton
Sir Isaac Newton died at Kensington, London, England.