No
Another Answer:-
Yes sometimes it is possible as for example: 4a/8b can be simplified to 1a/2b
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You multiply out brackets, remove common factors from fractions, combine like terms.
There is no limit to the number of variables.
No, you cannot.
To simplify an expression you must combine the variables and the constants. Then write the simplified version of the expression so that the expression isn't solved, just simplified. 1a+2(a+5)=2a+7
You cannot simplify 5/16. 5 and 16 do not share any whole number factors, therefore it is impossible to simplify them.