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Since the advent of next generation sequencing (NGS) technology three decades ago, enormous progress has been made in the fields of Biology and medicine. NGS is a deep, high-throughput, massively parallel or deep sequenced DNA or RNA sequencing technology that has revolutionized genomic research. It is usually used to study genetic variation associated with diseases or other biological phenomena.
Currently, NGS technology has been widely used in clinical practice to improve patient care. Compared to traditional Sanger sequencing (first-generation sequencing technology), NGS captures a broader spectrum of mutations and uncovers the human genome without bias. For example, NGS technology unravels the genetic basis of unexplained developmental delays by sequencing affected children and their parents to reveal harmful de novo mutations. Combining these molecular data with detailed clinical phenotypic information, novel genes that mutate in affected children with similar clinical characteristics have been successfully identified.
NGS technology has also been used in the current research of some incurable diseases, changing the way a disease is diagnosed, and providing scientists and physicians with fact-based guidelines for the treatment. Recently, a team of researchers from Singapore demonstrated that the next generation sequencing test can detect HIV drug resistance mutations that cannot be identified by the traditional test. This test may play a critical role in helping clinicians to optimize HIV treatment plans, as well as contributing to public health initiatives to minimize the development of global resistance to antiretroviral drugs. Next generation sequencing technology has opened a broad new area of research with the potential to revolutionize personalized cancer medicine. (Go Creative Biolabs)
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What is the next number in the sequence 5 10 30 120?
The next number in the sequence is 480
What is the next number in the sequence 20 5 30 6 42 7?
The next number in the sequence will be 56.
What is next in this sequence 12 5 20 1 18 4?
25 is the next number that appears in that sequence.
What is the next number in the sequence 18 15 5 39 36?
The next number could be 26 The next number could be 12 - - - - - - - - - The next number that is in the sequence is 12.
What number is next in this sequence 2 9 5 13 10 19 17?
The next number in the sequence is 27.
How is find the gene sequence of an monoclonal antibody found?
To find the gene sequence of a monoclonal antibody, the antibody must first be produced by hybridoma cells cultured in the laboratory. Next, the RNA is extracted from these cells and the gene encoding the antibody is reverse transcribed into DNA. This DNA can then be sequenced using techniques such as Sanger sequencing or next-generation sequencing to determine the gene sequence of the monoclonal antibody.
What is a copy of DNA containing a gene?
A copy of DNA containing a gene is called a gene sequence or genetic code. This sequence provides the instructions for making a specific protein or function within an organism. It is passed down from one generation to the next through reproduction.
What does ngs go mean?
"NGS" most likely refers to Next-Generation Sequencing, a high-throughput technique used to sequence DNA or RNA. "GO" could stand for Gene Ontology, a system for classifying genes and their functions. Together, "NGS GO" might refer to the analysis of gene expression data generated through next-generation sequencing using gene ontology terms.
Does the promoter on a DNA sequence lie next to the 5' or 3' end?
The promoter typically lies next to the 5' end of a gene on the DNA sequence. It is the region where RNA polymerase binds to initiate transcription of the gene.
In evolutionary terms an organisms fitness is measured by its?
contribution to the gene pool of the next generation
What are the release dates for Gene Simmons Family Jewels - 2006 Next Generation Rock Star 1-2?
Gene Simmons Family Jewels - 2006 Next Generation Rock Star 1-2 was released on: USA: 7 August 2006
What is the definition of heriditray?
Hereditary means descending by inheritance from one generation to the the next.
Why don't gene frequencies change from one generation to the next?
Gene frequencies may remain stable between generations due to factors such as random mating, large population size, absence of gene flow, absence of mutations, and absence of natural selection. When these factors are in play, genetic equilibrium is maintained, and gene frequencies do not change significantly from one generation to the next.
How can one trair disappear in one generation and then reappear in a later generation?
A trait can disappear in one generation due to a recessive gene being masked by dominant genes. When two carriers of the recessive gene have children, there is a 25% chance the trait will reappear in the next generation as the recessive gene is expressed. This is known as genetic recombination through Mendelian inheritance.
What is the meaning of thr word genes?
Genes are segments of DNA that contain the instructions for building proteins, which in turn determine an organism's traits and characteristics. Genes are inherited from parents and are responsible for passing down genetic information from one generation to the next.
What does the phrase successive generation mean?
Successive generation refers to the sequence of offspring produced from one generation to the next within a species. It signifies the continuous passage of genetic material and traits from parent to offspring.
What is the definition of a common difference in a sequence?
common difference is the difference in every two consecutive numbers in the sequence .. or in the other way around, its the number added to a number that resulted to the next number of the sequence ..
