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Yes, but the matrices get fairly complicated.

Example:

aW + bX + cY + dZ = e

fW + gX + hY + iZ = j

kW + lX + mY + nZ = o

pW + qX + rY + sZ = t

|a b c d| | W | | e |

|f g h j| | X | | j |

|k l m n| | Y | = | o |

|p q r s| | Z | | t |

Solving for W is not easy...

|e b c d|

|j g h j|

|o l m n|

|t q r s|

----------

|a b c d|

|f g h j|

|k l m n|

|p q r s|

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Q: Does Cramers rule apply to systems of 4 equations with 4 variable or higher?
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