The exclamation point is called a factorial.
ex. 5!=5x4x3x2x1
10!=10x9x8x7x6x5x4x3x2x1 etc.
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You isolate variables in math because the point of an equation is to solve for the variables. By isolating the variables you have learned what that variable stands for and thus solved the equation.
an exclamation point !
It can have the regular meaning of an exclamation point - that you want to draw the attention to the number. However, in math it may also refer to the factorial of the number. It means that you multiply all positive integers up to that number together. For example:5! = 1 x 2 x 3 x 4 x 5 = 120.
An exclamation mark after a number is the symbol for the factorial function.
Not always - it depends on the context. There would be an exclamation point if it was being shouted or if it was being said in an exclamatory manner.