8 times. (2 * 8 = 16)
If you subtract "2" 8 times this will leave you with 0.
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As many times as you want. If what you mean is, how many times can you subtract 2 from 46 before you hit zero (that is, "how many times does two go into 46") the answer is 23.
You can subtract 2 from 21 a total of 10 times. This is because each time you subtract 2, you are left with 19, and you can repeat the process until you reach 1. Mathematically, this can be represented as 21 - 2 = 19, 19 - 2 = 17, and so on until you reach 1.
2 goes into 32 ... 16 times
16 / 8 + 2 * 5 - 21 / 7 = 2 + 10 - 3 (multiplication and division first) = 9