There are none.
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Demonstrate an understanding of the world as a set of related systems by recognising that the business organisation is one of the systems in this network of systems and that problemsolving-contexts in an organisation do not exist in isolation
None, there are no disadvantages.
Advantages can become disadvantages. Sometimes the disadvantages become the advantage. So, who's to say if it was an advantage or a disadvantage?
The disadvantages are that the calculations required are not simple and that the method assumes that the same linear relationship is applicable across the whole data range. And these are the disadvantages of the least squares method.
Only a person who does not understand mathematics is disadvantaged. Mathematics in itself has no disadvantages.