Each number describes the previous one: 10 means there is "one zero" in the previous number; 1110 means that in the previous number there is "one one, followed by one zero", etc.
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A single number, such as 2481020, cannot define a sequence.
The number that comes after 5099 is 5100. In the decimal number system, each number is followed by the next consecutive number in a sequence. Therefore, when counting up from 5099, the next number in the sequence is 5100.
One number does not make a sequence (nor a series).
The next number is 0
You are multiplying each number in the sequence by -2. Therefore, the next number in the sequence after 32 is -64.