That is going to vary tremendously depending upon the design of the home. Noone could give you an accurate answer without reviewing the plans. If you have the plans already, then take them to a licensed contractor or architect for a good estimate.
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It depends on the size of the bricks.
It depends on the one brick size
If you are using the red brick which are 4" x 8" you will need 4.5 bricks per square foot (just call it five.) 5 x 400 is 2000 bricks.
9" thick wall needs 12 bricks per square foor 13.5" thick wall needs 18 bricks per square foot. 18" thick wall needs 24 bricks per square foot Sender: Mr. Khayal Ahmed Memon Sub Engineer in USAID N.G.O
A 12 x 12 inch brick is 1 square foot. A 20 x 20 (foot) patio is 400 square feet, so you would need 400 bricks.. this assumes you are butting the bricks fairly tight, not leaving large seperations between them, etc...