Since the numbers 21 and 1600 share no common positive integer factors other than 1, the proper fraction 21/1600 is already expressed in its simplest form.
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21/5 is the simplest form.
21/10 is in its simplest form.
21/16 is in its simplest form.
4/21 is in its simplest form.
21/52 is the simplest form.