Since the numbers 45 and 49 share no common positive integer factors other than 1, the proper fraction 45/49 is already expressed in its simplest form.
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heh, well if you do the math you will find out and to my calculations, no it can not be simplified
16/45 cannot be simplified.
45/63 is 5/7 simplified
49/90 cannot be simplified.
98 over 198 simplified = 49/99