It depends on the alphabet:
There are also a few chinese characters that can loosely be described as polygons, such as: 凸凹口囗
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None in the Roman alphabet.
the alphabet has 26 letters in it
there are 33 letters in the cambodian alphabet
The latin alphabet for English has 52 letters, if you count both upper case and lower case. Otherwise, there no other alphabet with 52 letters.
The Latin alphabet varies in length, according to the language that uses it. If you mean the Latin version of the Latin Alphabet, it has 23 letters.