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Intravenous (IV)

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How route of administration drug can control bioavailability drug?

The route of administration of a drug can affect its bioavailability by influencing factors such as first-pass metabolism, absorption rate, and drug stability. For example, intravenous administration bypasses the first-pass metabolism, leading to higher bioavailability compared to oral administration where the drug may be metabolized before reaching the systemic circulation. Additionally, different routes can also affect the onset of action and duration of drug effects.


What is the bioavailability of a drug?

Bioavailability of a drug refers to the fraction of the administered dose that reaches systemic circulation in an unchanged form. It is a measure of the extent and rate at which the active ingredient is absorbed and becomes available at the site of action in the body. Bioavailability is influenced by factors such as route of administration, drug formulation, and first-pass metabolism.


What are the routes of administration of norcuron?

The administration route for norcuron is intravenously only. It can be mixed with lactated ringers, 0.9 percent NaCl solution, 5 percent glucose in saline, 5 percent glucose in water, and sterile water for injection.


What is bioavilability in pharmacology?

Bioavailability in pharmacology refers to the fraction of a drug that reaches the systemic circulation and is available to produce an effect after administration. It is typically expressed as a percentage and takes into account how much of the administered dose is absorbed and becomes available to the body. Factors like drug formulation, route of administration, and first-pass metabolism can affect a drug's bioavailability.


Is oral route of administration safer?

Yes the oral route for drug administration is the safest route.


What is the buccal route?

The buccal route is a method of drug administration where medication is placed between the gums and the inner lining of the cheek, allowing for absorption through the mucous membranes in the mouth. This route bypasses the digestive system and liver metabolism, resulting in faster onset of action. It is commonly used for certain medications, such as those for pain management or hormone replacement therapy. Buccal administration can enhance bioavailability and provide a convenient alternative to oral or injectable routes.


What is the a dvantages and disadvantages for rectal routes of administration?

The rectal route of administration offers several advantages, including bypassing first-pass metabolism, which can enhance the bioavailability of certain drugs. It is also useful for patients who are vomiting or unable to swallow medications. However, disadvantages include variable absorption due to the rectal contents, potential discomfort or embarrassment for the patient, and limited drug formulation options. Additionally, some patients may have difficulty with self-administration or may refuse this route altogether.


What kind of administration is introducing drugs into the gastrointestinal tract?

The oral route of administration.


Which of the is not a gi tract route of drug administration?

Topical administration is not a gastrointestinal tract route of drug administration. It involves applying medication directly to the skin or mucous membranes for localized effects.


What is the difference between an injection that is given IM OR IV?

IM means Intramuscular route of drug administration, while IV means Intraveinal route of drug administration. IV route, takes the drug directly into the bloodstream resulting in 100% bioavailability instantly. Where as in IM route, drug is injected into muscle tissues, which holds the drug for a while and gradually releases into the bloodstream through the network bed of capillaries running across or surrounding the muscle tissue. In IM, the bioavailability may be slightly less than 100% of drug due to diffusion from muscle through tissue fluid and into the blood.


What is 'first pass mechanism' in pharmacology?

In pharmacology, the first-pass mechanism refers to the initial metabolism of a drug in the liver before it reaches systemic circulation. This process can significantly reduce the bioavailability of the drug, meaning less of the drug reaches its target site in the body. It is an important consideration when determining drug dosage and route of administration.


Is mouthwash chloherxidine route of administration topical?

yes