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Signal-to-cutoff ratios (S/C ratios) are used in immunoassays to evaluate the strength of a signal relative to a predetermined cutoff value, which distinguishes positive and negative results. A higher S/C ratio indicates a stronger signal, suggesting a higher concentration of the target analyte, while a lower ratio may indicate a negative or inconclusive result. This metric is crucial for assessing the sensitivity and specificity of diagnostic tests. S/C ratios help ensure reliable interpretations of test results in clinical and research settings.

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Is there a statistical test to assess the difference between two ratios. I have numbers which are ratios and want to test whether there is a statistical difference between them?

You can use the z test for two proportions. The link below will do this test for you.


What are the uses of probability ratio?

With probability ratios the value you get to describe the strength of the relationship when you compare (A given B) to (A given not B) is not the same as what you get when you compare (not A given B) to (not A given not B). This is, IMHO, a big problem. There is no such problem with odds ratios.


How is a weighted loss ratio calculated?

you add your weighted premiums and divide by your weighted claims. (you do not weight the loss ratios )


Why are the larger t-ratios more likely to be statistically significant?

Larger t-ratios indicate a greater difference between the sample mean and the null hypothesis mean relative to the variability in the data. This suggests that the observed effect is less likely to be due to random chance. As a result, larger t-ratios are more likely to exceed the critical value for significance, leading to a higher probability of rejecting the null hypothesis. Thus, they often indicate stronger evidence against the null hypothesis.


Compare and contrast ratios and rates?

Ratios and rates are mathematical derivations. A ratio is an index comparing fractionally indexing multiple quantities vis-Ã -vis one other. A 1 to 1 (1:1) ration of milk to water would mean equal quantities of each. A rate is a measure of quantity over time. Rates can include speed and the volume of fluid movement.

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