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Free coagulase is an extracellular toxin that reacts with a thrombin-like, thermostable substance known as coagulase-reacting factor (CRF) or serum factor. The reaction of coagulase and CRF will lead to the formation of coagulase-CRF complex where this complex indirectly changes frbrinogen to fibrin (clotting factor) and hence will form a fibrin clot. Furthermore, it is also use as the primary indicator of virulence among staphylococci. Its clinical significance is that when doing the coagulase tube test, the free coagulase will react with the plasma in the tube and hence convert the fribrinogen into fibrin which lead to fibrin clot formation in the tube. This is shown after one day of incubation of the tube, when the tube being invert, the plasma will not go down showing that it is clotted.
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What was the significance of 36 30?
To separate slave and free states
What is the significance of change in position over change in time?
To different individuals, it may or may not have any significance. The quantity is typically referred to as "speed", and you're free to decide for yourself whether it has any relevance in your life.
What is the adjective and adverb of significance?
The adjective of significance is significant.The adverb of significance is significantly.
What is the significance of 1.45?
what is the significance 1.45% ?
What significance does the invention of the symbol zero have for today?
No significance:-)>
What is difference between tube coagulase and slide coagulase test?
tube coagulase is done in test tube while slide coagulase is done on slide.thnk you all! cheeres!
Why is it important to use fresh cultures in a coagulase test?
Coagulase is a protein enzyme. It is important to use fresh cultures in a coagulase test because coagulase expression is highest during the log phase of growth.
What is bound coagulase?
Coagulase is a protein produced by several organisms, namely Staphylococcus and in laboratories is used to distinguish different isolates.Bound coagulase is part of the larger family of MSCRAMM.
What are 2 types of staphylococal coagulase?
2 types of staphylococal coagulase are 1.staph.epidermidis/albus2.staph.aureus
What is a CNS and what do they do?
coagulase-negative staphylococci (CNS)
Is coagulase test a microbiological test?
YES
What is the carbohydrate profile for S epidermidis?
coagulase
What does the enzyme coagulase do?
The coagulase enzyme activates prothrombin, which causes fibrin formation around the bacteria (ie Staph aureus), protecting it from phagocytosis. Of all 3 pathogenic staphylococcal species, only Staph aureus is coagulase positive.
What makes coagulase important for a pathogen?
There is some controversy about whether coagulase is a virulence factor, but one way coagulase contributes to pathogenicity is that it binds prothrombin to form staphylothrombin, which then cleaves fibrinogen to form fibrin clots in which the bacteria can live and avoid phagocytosis by neutrophils.
What is a coagulase test used for?
Rabbit plasma, sometimes with EDTA added
The historical significance of the free silver?
yes
Micrococcus luteus produces the enzyme coagulase?
Micrococcus luteus is a Gram-positive, to Gram-variable, nonmotile, spherical, saprotrophic bacterium that belongs to the family Micrococcaceae. It produces coagulase which is a protein enzyme that enables the conversion of fibrinogen to fibrin.
