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The most significant byte (MSB) of a positive binary number is the decimal value of the left-most bit.

For example, the binary number 10111001011 is 11 bits, meaning it's 11 digits long. Thus, the decimal value of the left-most bit, the MSB, is 1 X 210 = 1024. The reason why it's not 1 X 211 is that the decimal value of the right-most bit is represented by raising 2 to the 0th power, not the first power. In this case, the right-most bit has a decimal value of 1 X 20 = 1.

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Q: What is the MSB of a positive binary number?
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Difference in 1's and 2's Complement?

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