So there are two points, (4,2) and (5,1).
You find the slope by taking the difference in the rise over the difference in the run.
The rise is calculated from the y coordinates, which are the second numbers. The run is calculated from the x coordinates, which are the first numbers in the set.
So, the rise would be 1 - 2, or -1.
The run would be 5 - 4, or 1.
-1 / 1 = -1. The slope is -1.
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The line is vertical and so the slope is undefined.
The slope is -2/3.
Points: (0, 0) and (4, 1) Slope: 1/4
No
Points: (14, 5) and (20, 4) Slope: -1/6