It means that for every three units of distance that you move to the right you move one unit up (equivalently, 3 left and 1 down).
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If you mean points of (1, 5) and (-1, -1) then the slope works out as 3
Points: (1, -3) and (2, -5) Slope: -2
Points: (-2, 3) and (1, 1) Slope: -2/3
Points: (-1, -1) and (3, 15) Slope: 4
Points: (-1, -1) and (-3, 2) Slope: -3/2