Assuming you mean 5 inches on an edge:
Each face will be 5"x5" with an area of 25 in2. Since a cube has 6 faces, the total surface area will therefore be 6x25 in2 = 150 in2
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The surface area of a cube with an edge length of 5 inches is 150 square inches.
The surface area of a box, which is a cuboid, depends on its length, width and height. A cube is a special type of cuboid in which the length , width and height are all the same.
It is: 6*(5*5) = 150 square inches
It is: 5*5*5 = 125 cubic cm
Ok, say you have a large cube with edges of one inch each. If you cut that cube into eight separate cubes, each with a side length of .5 inches, the surface area is increased, because now more of the original substance is exposed.