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Motrin contains no acetaminophen. The main ingredient being ibuprofen (also what Advil is made of). The two have no known negative effects when taken together.

Don't take them at the same time, alternate them. To be completely safe, consult with your doctor or pharmacist before taking any drugs at the same time.

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Q: Can you take Motrin 400 mg and Tylenol 325 mg together?
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