The answer will depend on the measurement units for the tiles. Are they 2 inch x 2 inch or 2 ft x 2 ft? Since you have not bothered to provide that crucial bit of information, I cannot provide a more useful answer.
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Tiles that are two feet on a side cover 4 square feet. 378 of them cover 1512 square feet.
76.6 tiles
67 tiles.
157 18 by 18 tiles are needed to cover 352 square feet.
You will need at least 67 tiles. This will cover 150.75 square feet.