Tiles that are two feet on a side cover 4 square feet. 378 of them cover 1512 square feet.
If that is 2' x 4' it would cover 800 square feet. If it is 2" x 4" it would cover about 5.5 square feet.
If the tiles are 1 foot squares, it will take 1,650 of them to cover 1,650 square feet. If the tiles are 16 inch square (1-1/3 square feet, each), then it would take 1,238 tiles.
Approximately 73 square feet.
Two tiles will suffice since they will cover 36 square feet.
Since a 12x12 tile is one square foot, then 38 12x12 tiles will cover 38 square feet.
I'm going to assume that the tiles are square inches, rather than square feet. But they can be converted to 3 square feet, which means 70 of them would cover the space if it were perfectly rectangular. Get 80 to be safe.