There are 252 combinations.
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210
Three sets
6 if order doesn't matter
It looks like you are asking how many combinations of 6 numbers are there in the 28 numbers 1 through 28. This is known as the number of combinations of 28 things taken 6 at a time. The answer is 28!/(6!22!) (n! means n factorial, which is the product of all the integers from 1 to n). I get 376,740 if I haven't made an error in arithmetic.
from the numbers 4567 we can have 24 numbers