If the six digits are all distinct and either they are all positive or a leading zero is permitted, then the answer is 6! = 6*5*4*3*2*1 = 720
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5040 numbers can be made.
There are 9 x 10 x 10 x 10, or 9000 four-digit number that can be formed if the leading digit cannot be zero.
There are only two smaller 3-digit numbers and both of them have repeated digits.
1339
It is 120 if the digits cannot be repeated.