Complement is part of the innate immune system (one you are born with). It consists of small protein molecules that circulate in the blood stream. Complement has three pathways, The classic pathway; The alternative pathway; and the lectin pathway. In the classical pathway, complement is activated by triggers such as the binding of an antigen to an antibody. In the alternative pathway, Complement is part of the natural immune system and complement assist in the opsonization, or the marking of an antigen to be destroyed by a phagocyte. This like the antigen has been marked with black marker so that a killer cell (phagocyte-cell eater) can find it to eat it. Finally the lectin pathway, which is similar to the classical pathway in terms of structure but this pathway starts with lectin or ficolin binding to sugars. After activation complement can trigger any number of events such as opsonization, chemotaxis, inflammation, and lysis (breaking) of cells.
The complement system is a series of about 20 proteins that are involved in a cascade effect during an immune response. Complement is generally divided up into 3 pathways: classical, lectin, alternate. The classical pathway involves a complement protein binding to an antigen-antibody complex (and thus its role in adaptive immunity). Whereas in the alternate pathway, complement (C3) binds directly to the foreign cell( usaully bacteria). Thus its repsonse is non specific and therefore is also part of the innate imune system.
Complement activation is a cascade of proteins in the immune system that helps to opsonize pathogens for phagocytosis, recruit inflammatory cells, and directly lyse target cells. It can be activated through three pathways: classical, lectin, and alternative pathways, and plays a critical role in innate immunity.
You can monitor Lectin by reading up on the foods that contain it and how much you are allowed to consume. Your doctor will inform you on your medications and the Lectin.
An agglutinating lectin is a protein that can bind to specific sugar molecules on the surface of cells or pathogens, causing them to clump together or agglutinate. This agglutination can help facilitate the removal of the target cells by the immune system.
Yes, cell membrane mannose can be used for adherence in certain biological processes. Mannose-specific adhesins on pathogens can recognize and bind to mannose residues on host cell membranes, facilitating adherence and colonization. This interaction is important in host-pathogen interactions and can influence infection and disease progression.
immunotoxin
The active poison in the castor bean is ricin, a deadly water-soluble protein called a lectin.
For Type Bs, the biggest factors in weight gain are corn, buckwheat, lentils, peanuts and sesame seeds. These foods have different lectin that affect the efficiency of the metabolic process, resulting in fatigue, fluid retention, and hypoglycemia. The gluten lectin in wheat germ and whole wheat products also adds to the problems cause by other metabolism-slowing foods.
Janus Michael Rini has written: 'Structural analysis of carbohydrate recognition by pea lectin: an x-ray crystallographic study'
C4bC2a is a C3 convertase, which is stabilized by the surface of the acvtivator (activating substance). It only will cleave C3, and can only be activated in one of three pathways: classical, lectin and alternative.
Iara De Messias-Reason has written: 'Mannose-binding lectin in the innate immune system' -- subject(s): Mannose, Natural immunity, Lectins