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Does C2a or C2b bind C4b in classical pathway of complement activation?
C2a
The complement of an angle is twice the measure of the angle what is the measure of the complement?
The complement is 60 degrees.
What kind of complement is tourist?
objective complement
What are the example of modifier complement?
example modifier and complement
What does complement mean in probability?
The complement of an event occurring is that it does not occur.
Which complement protein is the key to activating the alternative pathway of complement activation?
Factor B is the key complement protein that helps activate the alternative pathway of complement activation. It forms a complex with Factor D and is cleaved by Factor D to produce the active fragment, which leads to further activation of the alternative pathway.
What is a mechanism of nonspecific resistance?
activation of the complement via the alternative pathway
Does C2a or C2b bind C4b in classical pathway of complement activation?
C2a
How does membrane cofactor protein stop complement activation?
Membrane cofactor protein (MCP) acts as a cofactor for Factor I, which degrades C3b and C4b proteins, thus preventing the amplification of complement activation. By accelerating the decay of C3 convertases, MCP helps regulate the complement system and protect host cells from excessive complement-mediated damage.
What is the chief ammunition used against cellular antigens?
complement fixation and activation of the antibody
The binding of an antigen to an antibody can result in?
neutralization of the antigen, agglutination or precipitation, and complement activation.
Why is the alternative pathway of complement useful in the early stages of an infection?
It does not rely on activation by antibodies.
Which of the following is an effect of complement activation?
Complement activation can lead to direct killing of pathogens by forming pores in their cell membranes, promoting inflammation by recruiting immune cells to the site of infection, and facilitating clearance of immune complexes and cellular debris.
What is complement activation?
Complement activation is a cascade of proteins in the immune system that helps to opsonize pathogens for phagocytosis, recruit inflammatory cells, and directly lyse target cells. It can be activated through three pathways: classical, lectin, and alternative pathways, and plays a critical role in innate immunity.
Why IGM is so much efficient in activating complement than IgG?
IgM is more efficient in activating complement than IgG because of its larger size and pentameric structure, which allows for more binding sites and better clustering of complement proteins. This leads to a more robust activation of the complement cascade and increased inflammation and opsonization.
What would be the likely outcome if a microbe could prevent the activation of C3 in the complement cascade?
If a microbe can prevent the activation of C3 in the complement cascade, it would likely evade the host immune response and avoid being targeted for destruction. This evasion strategy could help the microbe establish infection and cause disease without being effectively eliminated by the immune system.
Which immune response would not occur when staphylococcus aureus enters the bloodstream?
The specific immune response that may not occur when Staphylococcus aureus enters the bloodstream is the activation of the complement system. This response involves a series of proteins that help to eliminate invading microorganisms, but certain strains of Staphylococcus aureus possess proteins that can inhibit or evade complement activation, allowing the bacterium to evade immune detection and destruction.
