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The origin for transmutation circles came from the anime FullMetal Alchemist. Transmutation circles are formed using the symbols and keys of real life alchemy used during the Middle Ages. Their meanings and the meaning interpreted into the show are very similiar, but that is only done to encourage the belief of it's existence. Creating works that can be linked to our past or everyday lives tends to make us believe in it's existence. So, to answer your question, transmutation circle do not work. They were created to endorse a now famous Japanese anime. and that is all they will ever be.
You channel your chi into a transmutation circle when you have the ingredients to make what you want. Than think about what you want to make.
Yes. The circles can be of different size. These are called concentric circles.
A cylinder has two circles as its bases.
concentric circles