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It depends upon how you got to the 12, for example:

28.6 - 16.6 = 12.0

Because each of the numbers that was used to get to the 12 had 3 significant figures, you should write the 12 with three significant figures also.

However:

29 - 17 = 12

In this case, each of the numbers that was used to get to 12 had only 2 significant figures, so use only 2 significant figures in the 12.

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Q: What is 12 in significant digit?
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