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41975308260
If that is the only criteria then the lowest number is 456789, what you allready have.
1,000,460 with remainder 250.
zero
345688904655445456545655 x 1234567890 = 4.26776422 × 10^32 This is approximately 346 sextillion times 1.2 billion. So in broad strokes, 415.2 nontillion.