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Q: What is a complement binding site?
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Complement binding sites are located on?

Fc fragment of antibody


What is a binding site?

The binding site is where a specific binding molecule and a specific receptor protein can combine. This combination can only occur at the binding site. All in the 9th grade text book


The binding of an antigen to an antibody can result in?

neutralization of the antigen, agglutination or precipitation, and complement activation.


What is the site of oxygen binding on hemoglobin?

You have Iron atoms in hemoglobin. This atom is the binding site for oxygen in case of hemoglobin.


Which molecule has a binding site for calcium?

Calmodulin is a calcium-binding protein that has a binding site for calcium ions. It is involved in the regulation of various cellular processes by binding calcium and transducing the signal to downstream effectors.


Which molecule covers the binding site?

Proteins can cover the binding site of a receptor and prevent another molecule from binding to it. This interaction can inhibit the receptor's activity and affect cellular signaling pathways.


What Is the difference between antigen binding site and paratope?

Antigen binding site or epitope is a part of an antigen that is recognized by the antibody. Paratope is a part of an antibody that binds on epitope.


Why IGM is so much efficient in activating complement than IgG?

IgM is more efficient in activating complement than IgG because of its larger size and pentameric structure, which allows for more binding sites and better clustering of complement proteins. This leads to a more robust activation of the complement cascade and increased inflammation and opsonization.


What is the difference between an allosteric enzyme and a non-allosteric enzyme?

An allosteric enzyme has multiple binding sites that can be used to modulate its activity through the binding of effectors or ligands, whereas a non-allosteric enzyme typically only has one active site. Allosteric enzymes can exhibit cooperativity, meaning that binding at one site affects binding at another site, while non-allosteric enzymes do not show this behavior.


The region of a protein that binds a ligand?

The region on a protein that binds a ligand is known as the binding site. This site is typically composed of specific amino acids that interact with the ligand through various chemical bonds and molecular interactions. The binding of the ligand to the protein's binding site is crucial for the protein's function and activity.


Difference between active site and binding site?

Binding site is anywhere which something (such as a protein) can bind to. An example would be the upper flanking regions which contain binding sites thattranscription factors bond with during transcription. The active site is more specific to enzymes and refers to the site where the enzyme functions. It is the specific contours of this active site which give the enzyme its specific function (see how enzymes are substrate specific).


What is the function of the complement cascade called opsonization?

Opsonization is a process in which pathogens are marked for destruction by phagocytic cells. It involves the binding of complement proteins to the surface of the pathogen, making it easier for phagocytes to recognize and engulf the pathogen.