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The bits in a numeric value like

00000000 00110011

have a decimal value based on the bit position. The most significant bit is the one that has highest decimal value and is the left most bit. The right most bit is the least significant bit.

High-order bits are the half of the number of bits that have the highest values, the left most bits in the 16 bit value above The low order bits in this case are the right most bits.

This should not be confused with bit placement in memory/cpu registers. Intel/AMD cpus are little edian, meaning that the most significant part is physically right and the lest significant is left most (the bits are not in reverse order). Google for a more detailed info.

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Q: What is meant by the term low-order bits and high-order bits most significant bit?
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