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Phosphodiesterase breaks down cAMP. While at first glance this may appear to be a problem, it is quite the opposite. Because of the amplification effect, most hormones need to be present only briefly to cause the desired results.

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Q: What is the function of Phosphodiesterase?
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When phosphodiesterase inhibited what happens?

itwhat happens when phosphodiesterase is inhition


What is function of phosphodiesterase?

Phosphodiesterase breaks down cAMP. While at first glance this may appear to be a problem, it is quite the opposite. Because of the amplification effect, most hormones need to be present only briefly to cause the desired results.


What does phosphodiesterase break down cAMP into?

Phosphodiesterase breaks down cAMP into AMP (adenosine monophosphate).


What terminates cell signaling by inactivating cAMP?

Phosphodiesterase


What is the medical definition of phosphodiesterase?

Phosphodiesterase in medical terms means a class of enzymes that are found in nucleic acids. They break down and produce even smaller nucleotide units.


What is the enzyme that inactivates cAMP?

cAMP is inactivated by the enzyme phosphodiesterase (PDE), which breaks down cAMP into its inactive form, AMP. This process regulates the signaling pathway controlled by cAMP in cells.


Which intracellular substance degrades cAMP thus inactivating the response to a hormone?

Phosphodiesterase degrades cAMP in the cell, leading to the inactivation of the response to a hormone. This enzyme is crucial in regulating signal transduction pathways by breaking down cAMP into AMP.


What intracellular substance degrades cAMP and inactivating the response to a hormone?

Phosphodiesterase is the intracellular substance that degrades cAMP, leading to the inactivation of the cellular response to a hormone. This enzyme breaks down cAMP into AMP (adenosine monophosphate), thereby terminating the signal transduction pathway initiated by the hormone.


What effect would an inhibitor of phosphodiesterase activity would have?

An inhibitor of phosphodiesterase activity would increase the levels of cyclic AMP and/or cyclic GMP in the cell. This may lead to prolonged signaling cascades, affecting various physiological processes such as smooth muscle relaxation, platelet aggregation, and neurotransmitter release.


What is the mechanism of action of methylxanthine as a bronchodilator?

Methylxanthines like theophylline work as bronchodilators by inhibiting phosphodiesterase enzymes, particularly phosphodiesterase-4. By blocking these enzymes, methylxanthines prevent the breakdown of cyclic AMP which leads to smooth muscle relaxation in the airways, resulting in bronchodilation and improved airflow.


Viagra is effective in treating erectile dysfunction because this drug will?

decrease the activity of cyclic GMP phosphodiesterase in the smooth muscle cells of the penile blood vessels


Why is checking for phosphodiesterase inhibitors important prior to administration of nitrates?

phosphodiasterase inhibitors also act as a vasodilator and therefore if it is used with nitrates it will cause too much of vasodilation and the person can go into shock