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Phosphodiesterase breaks down cAMP. While at first glance this may appear to be a problem, it is quite the opposite. Because of the amplification effect, most hormones need to be present only briefly to cause the desired results.
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What is function of phosphodiesterase?
Phosphodiesterase breaks down cAMP. While at first glance this may appear to be a problem, it is quite the opposite. Because of the amplification effect, most hormones need to be present only briefly to cause the desired results.
What are pde 5 inhibitors used for?
A phosphodiesterase type 5 inhibitor, often shortened to PDE5 inhibitor, is a drug used to block the degradative action of phosphodiesterase type 5 on cyclic GMP in the smooth muscle cells lining the blood vessels supplying the corpus cavernosum of the penis. These drugs are used in the treatment of erectile dysfunction, and were the first effective oral treatment available for the condition. Because PDE5 is also present in the arterial wall smooth muscle within the lungs, PDE5 inhibitors have also been explored for the treatment of pulmonary hypertension, a disease in which blood vessels in the lungs become abnormally narrow.This is from Wiki
Is the relation a function?
Not every relation is a function. But every function is a relation. Function is just a part of relation.
The function f(x) x3 is called the function?
The cubic function.
If an inverse function undoes the work of the original function what does the original function's becomes the inverse function's domain?
Range
When phosphodiesterase inhibited what happens?
itwhat happens when phosphodiesterase is inhition
What is function of phosphodiesterase?
Phosphodiesterase breaks down cAMP. While at first glance this may appear to be a problem, it is quite the opposite. Because of the amplification effect, most hormones need to be present only briefly to cause the desired results.
What does phosphodiesterase break down cAMP into?
Phosphodiesterase breaks down cAMP into AMP (adenosine monophosphate).
What terminates cell signaling by inactivating cAMP?
Phosphodiesterase
What is the medical definition of phosphodiesterase?
Phosphodiesterase in medical terms means a class of enzymes that are found in nucleic acids. They break down and produce even smaller nucleotide units.
What intracellular substance degrades cAMP and inactivating the response to a hormone?
Phosphodiesterase is the intracellular substance that degrades cAMP, leading to the inactivation of the cellular response to a hormone. This enzyme breaks down cAMP into AMP (adenosine monophosphate), thereby terminating the signal transduction pathway initiated by the hormone.
What is the enzyme that inactivates cAMP?
cAMP is inactivated by the enzyme phosphodiesterase (PDE), which breaks down cAMP into its inactive form, AMP. This process regulates the signaling pathway controlled by cAMP in cells.
Which intracellular substance degrades cAMP thus inactivating the response to a hormone?
Phosphodiesterase degrades cAMP in the cell, leading to the inactivation of the response to a hormone. This enzyme is crucial in regulating signal transduction pathways by breaking down cAMP into AMP.
What effect would an inhibitor of phosphodiesterase activity would have?
An inhibitor of phosphodiesterase activity would increase the levels of cyclic AMP and/or cyclic GMP in the cell. This may lead to prolonged signaling cascades, affecting various physiological processes such as smooth muscle relaxation, platelet aggregation, and neurotransmitter release.
What is the mechanism of action of methylxanthine as a bronchodilator?
Methylxanthines like theophylline work as bronchodilators by inhibiting phosphodiesterase enzymes, particularly phosphodiesterase-4. By blocking these enzymes, methylxanthines prevent the breakdown of cyclic AMP which leads to smooth muscle relaxation in the airways, resulting in bronchodilation and improved airflow.
Viagra is effective in treating erectile dysfunction because this drug will?
decrease the activity of cyclic GMP phosphodiesterase in the smooth muscle cells of the penile blood vessels
Why is checking for phosphodiesterase inhibitors important prior to administration of nitrates?
phosphodiasterase inhibitors also act as a vasodilator and therefore if it is used with nitrates it will cause too much of vasodilation and the person can go into shock
