Their least common denominator is their product. Their greatest common denominator is infinite.
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Numbers having no common positive divisors other than one are relatively prime. In other words, the greatest common denominator of the numbers is one. Example: 24 and 25 are relatively prime.
The greatest common factor of two or more prime numbers is 1.
If the greatest common factor is 1, then the numbers are said to be co-prime or relatively prime.
As the numbers are all prime, the only factors each of them has are 1 and the number itself. Therefore the greatest, and only, common factor of two of more prime numbers is 1.
To simplify a fraction using prime numbers, find the prime factors of both the numerator and denominator. Then, divide the numerator and denominator by their common prime factors. Repeat this process until there are no common prime factors left. The resulting fraction will be simplified to its simplest form.