Numbers having no common positive divisors other than one are relatively prime. In other words, the greatest common denominator of the numbers is one.
Example: 24 and 25 are relatively prime.
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You might be thinking of relatively prime numbers. Two numbers are considered relatively prime if their GCF is 1. 4 and 9 are relatively prime.
It is, and always is relatively prime.
Any two different prime numbers are relatively prime because relatively prime numbers are sets of two or more numbers having 1 as their greatest common factor.
When two numbers are relatively prime, the LCM will be their product.
Use the prime factorizations to determine the GCF. If the GCF is 1, the numbers are relatively prime. If the two numbers have no prime factors in common, they are relatively prime.