One possible answer, based on
Un = (-11n4 + 138n3 - 605n2 + 1078n - 640)/8
would suggest that the next number is -50.
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16 is the next squared number.
3 4 5 6 The next number is 1 plus the previous number So the pattern rule is the next number is n + 1
The pattern is plus 7. So the next number used to be 1.
21
11